(1 customer review)

HPA-T Balancing Formula

Contegra by Sanesco Health is a broad-spectrum support formula for those who complain of anxiousness yet are fatigued due to poor sleep quality.

Ingredients support inhibitory and excitatory neurotransmitter production, adrenal and thyroid function, and methylation pathways. It also supplies cofactor and/or phosphorylated forms of B vitamins critical for proper neurotransmitter function.


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How it Works

Ingredients in Contegra by Sanesco Health support balance within the hypothalamic-pituitary-adrenal-thyroid (HPA-T) axis. This product also includes ingredients that support inhibitory activity as well as ingredients for excitatory activity to maintain inhibitory and excitatory balance. Healthy methylation is supported by multiple biologically active ingredients.

The NeuroSupport Blend™ (NSB) enhances absorption. Improved absorption allows for smaller doses and fewer capsules.

This product is often suggested after inhibitory support (Prolent, LentraTranquilent) has begun and offers a gentle transition to excitatory support. The dose of ingredients supporting excitatory neurotransmitters is higher in Procite-D than in Contegra. This product may be used in the Initial, Restoration or Maintenance phases on the path to patient wellness.


Inhibitory and excitatory neurotransmitter balance is critical for:

  • Mental and emotional health
  • Energy
  • Calm and relaxation

Adrenal health is important for:

  • Energy
  • Stress response
  • Resilience
  • Focus
  • Weight management
  • Menopause & andropause
  • Healthy blood sugar regulation
  • Mental and emotional health

Thyroid health plays important roles in:

  • Weight management
  • Energy
  • Digestion
  • Mood


  • L-theanine as Suntheanine® (standardized to >99%)Shown to promote relaxation by multiple mechanisms including antagonizing glutamate receptors, increasing the release of GABA, and decreasing norepinephrine levels in the brain.
  • N-Acetyl-L-Tyrosine Precursor to L-DOPA, the direct precursor to the catecholamines dopamine, norepinephrine and epinephrine. Acetylated for enhanced bioavailability.
  • Siberian Ginseng Extract (standardized to 0.8% eleutherosides) Eleutherococcus senticosus, an adaptogen thought to attenuate the effects of stress and fatigue.
  • Iodine (as potassium iodide)Essential component of T3 and T4 thyroid hormones.
  • Betaine (Trimethylglycine)Methylating agent that supports SAMe production/recycling. SAMe is a co-factor in epinephrine synthesis. Also acts as a source of glycine, an inhibitory amino acid neurotransmitter.
  • Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®) Cofactor in methylation reactions essential for synthesis of dopamine, norepinephrine and epinephrine.
  • Vitamin B6 (as pyridoxal-5’-phosphate):Active form of B6. Cofactor in conversion of L-DOPA to dopamine.
  • Vitamin B12 (as Methylcobalamin)  Coenzyme form of Vitamin B12. Methyl donor.
  • Pantothenic acid (as pantethine)Biologically active form of Vitamin B5; adrenal support nutrient.
  • NeuroSupport Blend™ (NSB) Proprietary mixture composed of Bioperine® and plant-based enzymes clinically proven to maximize nutrient absorption.

Supplement Facts

Serving Size: 1 Capsule
Servings per Container: 60 Capsules

Contegra Formula – 260.85 mg  

  • Vitamin B6 (as pyridoxal-5-phosphate)
  • Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
  • Vitamin B12 (as methylcobalamin)
  • Pantothenic Acid (as pantethine)
  • Iodine (as potassium iodide)
  • Betaine (Trimethylglycine)
  • L-theanine (as Suntheanine®)
  • N-Acetyl L-Tyrosine
  • Siberian Ginseng Extract (std. to 0.8% eleutherosides) (Eleutherococcus senticosus) (stem)

NSB™ Proprietary Blend – 102.5 mg
BioPerine® (Black Pepper Extract) (standardized to 95% piperine) (Piper nigrum) (fruit)

  • Protease
  • Amylase
  • Lipase

NSB™ is a trademark of Sanesco International Inc.


BioPerine® is a registered trademark and a product of Sabinsa Corp.


Suntheanine® brand L-Theanine is a registered trademark of Taiyo International, Inc. Suntheanine® is Generally Recognized as Safe (GRAS) & is Non-GMO Project Verified.


Quatrefolic® is a registered trademark of Gnosis S.p.A..

For more information regarding Sanesco and Targeted Nutritional Therapy TNT visit


Sanesco Health

Sanesco Health supplements and Targeted Nutritional Therapy (TNT), Communication System Management™ addresses the underlying causes of common health concerns with a proprietary system that analyzes neurotransmitter and hormone imbalances, provides personalized clinical data, and offers a targeted non-drug adjunct to existing treatment.
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1 review for Contegra

  1. Wesley

    Though I don’t typically believe in 5 star ratings, this product certainly deserves at least 4.5 stars! I have personally used Contegra for over 2 years and absolutely love it! Targeted Nutritional Therapy via NeuroLab testing has become a mainstay in establishing baseline neurotransmitter values while enabling our health coaches to implement neurotransmitter modulation protocols for all of our clients. I highly recommend taking your health and wellness to the next level by incorporating TNT into your program.

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