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5-Hydroxytryptophan

5-Hydroxytryptophan (5-HTP) by Thorne Enhances sleep and helps manage stress.

$35.00

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5-Hydroxytryptophan

5-Hydroxytryptophan (5-HTP) by Thorne, increases serotonin levels to promote restful sleep, manage stress, and decrease sugar cravings. It contains pyridoxal 5′-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.

Ingredient Information

Geometric Shape

Key Ingredients


Ingredient Amounts

Serving Size: 2 Capsules
Servings Per Container: 45
Name Amount
5-Hydroxytryptophan 100 mg
Vitamin B6 (Pyridoxal 5′-Phosphate) 6.8 mg
Other Ingredients: Hypromellose Capsule, Leucine, Microcrystalline Cellulose, Silicon Dioxide

How to Use

Take 1-2 capsules three times daily or as recommended by one of our health coach professionals.

Is 5-Hydroxytryptophan right for you?

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5-Hydroxytryptophan Details

The serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings. There are several ways to support a healthy serotonin level. L-tryptophan and 5-Hydroxytryptophan (5-HTP) are both precursors to serotonin.

However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system.

And 5-HTP can be taken with meals without reducing its effectiveness. 5-Hydroxytryptophan (5-HTP) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin.

Therefore, supplementation with 5-HTP will bypass the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase – which is the rate-limiting step in the synthesis of serotonin – and is a conversion that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.

5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream. Intestinal absorption of 5-HTP does not require the presence of a transport molecule, and its absorption is not affected by the presence of other amino acids; therefore, 5-HTP can be taken with meals without reducing its effectiveness.

5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue. Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.

To further facilitate serotonin production, Thorne’s 5-HTP formula contains pyridoxal 5′-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia. Each lot is thoroughly tested for contaminants, including Peak X, and is Peak X free.

Warnings

Allergy Warning

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Pregnancy Warning

If pregnant or nursing, do not use this product.

Interactions/Contraindications

5-Hydroxytryptophan should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.

Brand

Thorne

Our Mission

We believe personalized, scientific wellness can extend the duration of one's health span, create happier and healthier lives, and feel one’s best at every age and life stage. Our ambition is to empower individuals to live healthier for longer through personalized, scientific testing and solutions. With a deep portfolio of personalized offerings – testing that provides individualized data, educational resources, and products that support specific health goals and needs – Thorne is here at every age and life stage. Thorne is redefining what it means to live healthier for longer.

How we know our supplements work

At Thorne, being able to rely on the safety and efficacy of our nutritional supplement products is the motivating force behind our clinical trials program. Our confidence that each product we formulate and manufacture works in the body comes from extensive clinical research and medical literature that substantiate the presence of each ingredient in each formula. In addition to confirming the safety of our products, clinical research helps us better understand their efficacy. And it paves the way for new discoveries. The ultimate goal of our research partnerships is to help us fulfill our mission of solving the biggest challenges in health and wellness.
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5-Hydroxytryptophan 90ct by Thorne Front5-Hydroxytryptophan
$35.00
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