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SynaQuell +™ 357 g

SynaQuell + by Thorne offers a multi-ingredient nutritional supplement, formulated for post-impact brain support.


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SynaQuell +™

SynaQuell + by Thorne formulated to support brain health by enhancing cellular energy production and encouraging a healthy balance of inflammatory cytokines. NSF Certified for Sport®

Ingredient Information

Geometric Shape

Key Ingredients

Ingredient Amounts

Serving Size: 1 Scoops
Servings Per Container: 30
Name Amount
Beta Hydroxybutyrate (as Magnesium Beta Hydroxybutyrate) 750 mg
Betaine Anhydrous (Trimethylglycine) 85 mg
Coenzyme Q10 50 mg
Curcumin Phytosome (Meriva) 250 mg
DHA (Docosahexaenoic Acid) 375 mg
Glutathione (Reduced) 500 mg
L-Isoleucine 625 mg
L-Leucine 1.25 g
L-Valine 625 mg
Magnesium (Bisglycinate) 132 mg
Magnesium Beta Hydroxybutyrate 88 mg
Nicotinamide Riboside 415 mg
Riboflavin (as Riboflavin 5′-Phosphate Sodium) 100 mg
Trans-Resveratrol 125 mg
Other Ingredients: Carboxymethylcellulose Gum, Citric Acid, Flavors, Stevia Extract

How to Use

Mix 1 scoop with at least 12 ounces of water two times daily or as recommended by one of our health coach practitioners.

SynaQuell +™ Details

Good nutrition is essential for healthy brain function. The brain needs nutrients to provide energy to fuel the nerves, support neurotransmitter production, and protect against oxidative stress. That is why diet and supplementation are so important, particularly for an individual who needs post-impact brain support.

SynaQuell + is formulated with the best-researched nutrients for post-impact brain support. SynaQuell and SynaQuell + contain the same ingredients, but in different amounts. SynaQuell is for everyday maintenance, while SynaQuell + provides higher amounts of certain nutrients for shorter-term, post-impact support.

Key ingredients in SynaQuell + and their key benefits: 

  • Ketones, such as BHB, provide an alternate fuel source for both injured and uninjured brains.
  • BCAAs are important precursors to the neurotransmitters dopamine, serotonin, and norepinephrine.
  • CoQ10 phytosome provides post-impact brain support by reducing oxidative stress and supporting mitochondrial function.
  • DHA, an essential fatty acid found in high concentrations in membranes of the brain’s nerve cells, supports a healthy balance of inflammatory cytokines in the brain.
  • Nicotinamide riboside (NR) promotes NAD+ production, a key substance that protects brain cells.

A closer look at the ingredients in SynaQuell +

Beta-hydroxybutyrate (BHB) is a ketone. Why a ketone?

  • Ketones, such as BHB, supply 70 percent of the brain’s energy needs – and do so much more efficiently than glucose.
  • Ketones provide an alternate fuel source for both the injured and uninjured brain.
  • BHB is neuroprotective because it increases the production of new mitochondria, which in turn increases ATP (energy production) in brain and nerve cells.
  • BHB enhances cerebral blood flow.
  • BHB resists the damaging effects of oxidative stress, which can occur after a brain injury.

Branched-chain amino acids (BCAAs): 

  • BCAAs include leucine, isoleucine, and valine.
  • They readily cross the blood-brain barrier.
  • BCAAs and their metabolites have been shown to decline as a result of a mild impact to the brain.
  • In the brain, BCAAs serve as important precursors to the neurotransmitters dopamine, serotonin, and norepinephrine.

Coenzyme Q10 phytosome (Ubiqsome®)

  • Coenzyme Q10 benefits cognitive function and provides post-impact brain support by reducing oxidative stress and supporting mitochondrial function.
  • CoQ10 levels naturally drop with intensive exercise and during aging.
  • Ubiqsome provides 3-times better absorption than ordinary Coenzyme Q10.

Docosahexaenoic Acid (DHA):

  • Testing of the Omega-3 Index (the relative percentages of EPA and DHA in red blood cells) in college football players found insufficient levels of these important omega-3 fatty acids in this population.
  • DHA, which is found in high concentrations in the membranes of the brain’s nerve cells, supports a healthy balance of inflammatory cytokines in the brain.
  • DHA supports cognitive function and learning ability.
  • DHA is neuroprotective and supports healthy levels of brain-derived neurotropic factor (BDNF).

Nicotinamide Riboside:

  • Nicotinamide riboside (NR) is converted to NAD+ in the body. NAD+ helps convert food into energy and protects cells from damage.
  • NAD+ helps protect brain cells from injury.
  • NR supports learning, memory, and other cognitive functions.

Additional brain-supportive nutrients

  • Several brain-protective nutrients – reduced glutathione (antioxidant), riboflavin 5’-phosphate (active vitamin B2), and magnesium.
  • Botanical extracts – curcumin phytosome (Meriva®) and resveratrol – to support a healthy balance of inflammatory cytokines and up-regulate the release of the healthy-aging sirtuin proteins.

Because an athlete needs to know that his or her supplements are trustworthy and compliant, every batch of an NSF Certified for Sport® product is tested for compliance with label claims and to ensure the absence of more than 200 substances banned by many major athletic organizations, including stimulants, narcotics, steroids, diuretics, beta-2 agonists, and masking agents.


Proposition 65 Warning Notice for California Residents
Consuming this product can expose you to chemicals, including lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.

Allergy Warning
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Pregnancy Warning
If pregnant or nursing, do not use this product.

Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research revealed that curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided.

Additional Warning
Gas, bloating, or diarrhea may occur in some individuals taking magnesium supplements. This can occur at varying amounts depending on the individual and resolves when the amount is reduced.



Our Mission

We believe personalized, scientific wellness can extend the duration of one's health span, create happier and healthier lives, and feel one’s best at every age and life stage. Our ambition is to empower individuals to live healthier for longer through personalized, scientific testing and solutions. With a deep portfolio of personalized offerings – testing that provides individualized data, educational resources, and products that support specific health goals and needs – Thorne is here at every age and life stage. Thorne is redefining what it means to live healthier for longer.

How we know our supplements work

At Thorne, being able to rely on the safety and efficacy of our nutritional supplement products is the motivating force behind our clinical trials program. Our confidence that each product we formulate and manufacture works in the body comes from extensive clinical research and medical literature that substantiate the presence of each ingredient in each formula. In addition to confirming the safety of our products, clinical research helps us better understand their efficacy. And it paves the way for new discoveries. The ultimate goal of our research partnerships is to help us fulfill our mission of solving the biggest challenges in health and wellness.
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