AdreCor with SAMe 30ct


AdreCor with SAMe contains non-glandular ingredients important for adrenal health and mood.


AdreCor with SAMe

AdreCor with SAMe by Neuroscience contains non-glandular ingredients important for adrenal health and mood. In response to stress, the sympathetic nervous system (SNS) and hypothalamic-pituitary-adrenal (HPA) axis signal to the adrenals to release catecholamines (norepinephrine and epinephrine) and cortisol. 

AdreCor with SAMe „addresses prolonged stress associated with dysregulation of the HPA axis, which can affect catecholamine and cortisol levels.



  • Dopamine
  • Epinephrine
  • Norepinephrine


  • Cortisol

AdreCor and adrenal health

  • Contains amino acids and vitamins important for the synthesis of adrenal hormones and neurotransmitters.
  • 5-MTHF (from Quatrefolic®) and vitamin B12 are important for methylation processes including the synthesis of catecholamines.
  • Niacin, vitamin C, and 5-MTHF help protect and regenerate tetrahydrobiopterin (BH4) from oxidation.
  • Pantothenic acid is the precursor to coenzyme A (CoA), a coenzyme important for the energy production and hormone synthesis.
  • Cortisol induces the conversion of norepinephrine to epinephrine.
  • Catecholamines play an important role in mood, energy, memory, attention and cognition.

Catecholamines, stress, and fatigue

Catecholamines are involved in the central and peripheral stress responses.

  • The locus coeruleus is the primary source of norepinephrine in the brain and is involved in the initiation of the central stress response.
  • Depletion in catecholamines has been associated with fatigue and decreased vigor.
  • AdreCor with SAMe contains ingredients important for reducing stress-related fatigue and increasing norepinephrine.
  • In a randomized, double-bind, placebo-controlled study, Rhodiola Rosea was shown to significantly improve mental fatigue and general well-being under stress.
  • A meta-analysis demonstrated a significant increase in norepinephrine following the use of AdreCor with SAMe.


Amino Acid:

  • L-tyrosine
  • SAMe


  • Green tea leaf extract
  • Rhodiola (5% rosavins)


  • Folate
  • Magnesium
  • Niacin
  • Pantothenic acid
  • Vitamin B6
  • Vitamin B12
  • Vitamin C
  • Zinc


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