Perimenopause Complete

Perimenopause Complete provides a science-backed approach to addressing both the physical and emotional changes associated with perimenopause, the natural transition period leading up to menopause.

Formulated with clinically studied ingredients, once-daily Perimenopause Complete helps support sleep quality, mood balance, temperature regulation, and overall quality of life during perimenopause and postmenopause.

Studies on ingredients in the Perimenopause Complete formula showed noticeable support for the perimenopause transition within 1-2 weeks, and significant results with daily use beyond 4 weeks. Total menopause symptom severity on a scoring questionnaire was significantly improved after 12 weeks.

Benefits of Thorne Perimenopause Complete

Sleep and nighttime comfort 

• Supports restful sleep and reduces nighttime disruptions
• Helps decrease night sweats

Mood and emotional balance

• Helps support mood balance and emotional well-being
• Supports feelings of calm and nervous system balance

Physical comfort 

• Helps reduce hot flashes
• Supports joint comfort and overall physical well-being
• Decreases paresthesia, the ”pins and needles” sensation in hands and feet

Long-term wellness

• Supports healthy bone structure
• Helps alleviate vaginal dryness

Features of Thorne Perimenopause Complete

• Once-daily, 2-capsule serving
• Formulated with clinically studied ingredients
• Sustainably grown hops, harvested in Germany
• Plant-based support
• NSF Certified for Sport®

The perimenopause transition period leading up to menopause can begin earlier than many women expect – as soon as their late 30s in some cases – and it can last for years. Shifting hormones during this stage often leave women feeling confused, exhausted, and unheard.

Common signs and symptoms of perimenopause

• Difficulty falling or staying asleep
• Brain fog, trouble concentrating, or poor memory
• Hot flashes or night sweats
• Low energy and fatigue
• Mood changes, irritability, or anxious feelings
• Vaginal dryness and changes in libido

Clinically studied ingredients in Thorne Perimenopause Complete

EstroG-100® is a patented, herbal blend of three herbal extracts: Cynanchum wilfordii, Phlomoids umbrosa, and Angelica gigas – rooted in traditional Korean medicine. Across five clinical trials involving over 300 women from around the world, EstroG-100 was proven to significantly alleviate menopausal symptoms.

Why it matters: Clinically shown to significantly reduce overall severity of menopause symptoms.

Lifenol® is a patented hops extract, standardized to contain a phytoestrogen called 8-prenylnaringenin (8-PN) to alleviate menopausal hot flashes. This hops extract has been shown to support healthy bone structure in postmenopausal women.*

Why it matters: Supports hot flash relief and bone health.

Pyridoxal 5’ phosphate (P5P) is the active, tissue ready form of vitamin B6, an essential cofactor for neurotransmitters dopamine and serotonin.

Why it matters: Supports mood, emotional resilience, and restful sleep.

Why Thorne 

Perimenopause Complete is formulated with the scientific rigor Thorne is known for. Each ingredient is carefully selected, clinically studied, and tested through multiple rounds of quality control to ensure purity, potency, and consistency. Trusted by health-care practitioners, Thorne delivers evidence-based solutions to support women through every life stage.

Tested for quality you can trust

Because athletes need to know their supplements are trustworthy and compliant, every batch of an NSF Certified for Sport® product is tested for compliance with label claims and to ensure the absence of nearly 300 substances banned by many major athletic organizations.