Table of Contents
Methyl-Guard Plus®
Methyl-Guard Plus by Thorne provides superior methyl donors – trimethylglycine, 5-MTHF, and methylcobalamin – combined with bioactive vitamins B2 and B6 in a powerhouse formula for whole-body methylation support.
Ingredient Information
Key Ingredients
Ingredient Amounts
| Name | Amount |
|---|---|
| Betaine Anhydrous (Trimethylglycine) | 1.8 g |
| Folate (L-5-MTHF) | 5 mg DFE |
| Vitamin B12 (Methylcobalamin) | 3 mg |
| Vitamin B2 (Riboflavin 5′-Phosphate Sodium) | 90 mg |
| Vitamin B6 (Pyridoxal 5′-Phosphate) | 45 mg |
| Other Ingredients: Calcium (Citrate), Calcium Laurate, Hypromellose Capsule |
How to Use
Take 1-3 capsules daily or as recommended by one of our health coach professionals.
Methyl-Guard Plus® Details
Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.
Thorne’s Methyl-Guard Plus features betaine (trimethylgycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.
Benefits of Thorne’s Methyl-Guard Plus:
- Nutritional support for individuals who have MTHFR gene mutations
- Enhanced cellular energy production fights fatigue
- Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health
- Promotes fat metabolism and lean body composition
- Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep
- Promotes liver detoxification of many substances, including hormones like estrogen
Why is methylation important:
Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:
- Cardiovascular health
- Cellular energy production
- Fat metabolism
- Neurological function
- DNA production
- Liver detoxification processes
- Eye health
- Histamine balance
Who can benefit from Methyl-Guard Plus:
- Individuals with mutations to MTHFR and other genes that adversely affect methylation
- Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health
- Women seeking support for estrogen metabolism and bone health
- Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition
- Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables
Features of Methyl-Guard Plus:
- Betaine, also known as trimethylglycine, is a superior methyl donor
- The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations
- Active forms of vitamins B2 and B6 – key cofactors in methylation processes
- B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work
- Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard®
Warnings
Allergy Warning
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
Pregnancy
If pregnant, consult your health professional before using this product.
Interactions
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate’s anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
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