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Methyl-Guard Plus®

Methyl-Guard Plus by Thorne supports cellular energy production, heart health, brain function, and mood with nutrients that optimize methylation.

$57.00

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Methyl-Guard Plus®

Methyl-Guard Plus by Thorne provides superior methyl donors – trimethylglycine, 5-MTHF, and methylcobalamin – combined with bioactive vitamins B2 and B6 in a powerhouse formula for whole-body methylation support.

Ingredient Information

Geometric Shape

Key Ingredients


Ingredient Amounts

Serving Size: 3 Capsules
Servings Per Container: 30
Name Amount
Betaine Anhydrous (Trimethylglycine) 1.8 g
Folate (L-5-MTHF) 5 mg DFE
Vitamin B12 (Methylcobalamin) 3 mg
Vitamin B2 (Riboflavin 5′-Phosphate Sodium) 90 mg
Vitamin B6 (Pyridoxal 5′-Phosphate) 45 mg
Other Ingredients: Calcium (Citrate), Calcium Laurate, Hypromellose Capsule

How to Use

Take 1-3 capsules daily or as recommended by one of our health coach professionals.

Methyl-Guard Plus® Details

Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.

Thorne’s Methyl-Guard Plus features betaine (trimethylgycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.

Benefits of Thorne’s Methyl-Guard Plus:

  • Nutritional support for individuals who have MTHFR gene mutations
  • Enhanced cellular energy production fights fatigue
  • Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health
  • Promotes fat metabolism and lean body composition
  • Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep
  • Promotes liver detoxification of many substances, including hormones like estrogen

Why is methylation important:

Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:

  • Cardiovascular health
  • Cellular energy production
  • Fat metabolism
  • Neurological function
  • DNA production
  • Liver detoxification processes
  • Eye health
  • Histamine balance

Who can benefit from Methyl-Guard Plus:

  • Individuals with mutations to MTHFR and other genes that adversely affect methylation
  • Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health
  • Women seeking support for estrogen metabolism and bone health
  • Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition
  • Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables

Features of Methyl-Guard Plus:

  • Betaine, also known as trimethylglycine, is a superior methyl donor
  • The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations
  • Active forms of vitamins B2 and B6 – key cofactors in methylation processes
  • B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work
  • Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard®

Warnings

Allergy Warning

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Pregnancy

If pregnant, consult your health professional before using this product.

Interactions

5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate’s anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

Brand

Thorne

Our Mission

We believe personalized, scientific wellness can extend the duration of one's health span, create happier and healthier lives, and feel one’s best at every age and life stage. Our ambition is to empower individuals to live healthier for longer through personalized, scientific testing and solutions. With a deep portfolio of personalized offerings – testing that provides individualized data, educational resources, and products that support specific health goals and needs – Thorne is here at every age and life stage. Thorne is redefining what it means to live healthier for longer.

How we know our supplements work

At Thorne, being able to rely on the safety and efficacy of our nutritional supplement products is the motivating force behind our clinical trials program. Our confidence that each product we formulate and manufacture works in the body comes from extensive clinical research and medical literature that substantiate the presence of each ingredient in each formula. In addition to confirming the safety of our products, clinical research helps us better understand their efficacy. And it paves the way for new discoveries. The ultimate goal of our research partnerships is to help us fulfill our mission of solving the biggest challenges in health and wellness.
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Methyl-Guard Plus 90ct by Thorne FrontMethyl-Guard Plus®
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