Table of Contents
Methyl Folate
Methyl Folate supplies 1,000 mcg of biologically active folate called (6S) 5- methyltetrahydrofolate (5-MTHF).
5-MTHF is the naturally occurring, predominant form of folate commonly found in cells and is essential for overall health, as it participates as a cofactor in a reaction that involves the remethylation of homocysteine to methionine. Metafolin® is directly usable by the body and has been shown to be the only form of folate to cross the blood-brain barrier.
Functions
Folate is a water-soluble essential B vitamin found in many foods, including leafy green vegetables, citrus fruits and beans. Research has established that supplementation with folate before and during the first two months of pregnancy can support proper neurological development in the fetus.
Additionally, folate plays a key role in the metabolism of homocysteine. † Homocysteine is a sulfur containing amino acid that is created in the body from methionine, an essential amino acid derived solely from dietary intake. High plasma levels of homocysteine appear to injure the vasculature, impairing the functional abilities of endothelial and smooth muscle cells.
Indications
Methyl Folate is a useful dietary supplement for those individuals that prefer a high dose active form of folic acid called (6S) 5-MTHF.
Supplement Facts
Amount Per Serving
Serving Size 1 Tablet
Servings Per Container 60
- Folate (as Metafolin® L-5-MTHF) – 1,667 mcg DFE (1,000 mcg L-5-MTHF)
Other ingredients: Microcystalline cellulose, dicalcium phosphate, croscarmellose sodium, stearic acid, vegetable stearate and silica
Suggested Use
Adults take 1 tablet daily or as directed by a healthcare professional.
Side Effects
Doses of 5 mg or higher per day can cause abdominal cramps, diarrhea, and rash.
Storage
Store in a cool, dry place, away from direct light. Keep out of reach of children.






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