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Berberine Complex
Berberine Complex by Integrative Therapeutics is formulated to support the healthy balance of bacteria.
How it Works
Berberine is a constituent of some plants including Barberry (Berberis vulgaris), Oregon Grape (Berberis aquifolium), and Goldenseal (Hydrastis canadensis). Berberine Complex contains extracts of berberine-containing plants: barberry, Oregon grape, and goldenseal.
In addition to berberine, Goldenseal extract also contains other alkaloids such as hydrastine. Traditional use of herbs and extracts often rely on the complex nature of plants rather than isolated bioactive compounds. Berberine Complex is intended for traditional gastrointestinal support.
Berberine Supports Healthy Balance of Bacteria
Goldenseal, which contains alkaloids including berberine, has been traditionally used in North American for gastrointestinal support. Mechanistic studies in animals and cell culture models suggest berberine may modulate gut microbiota by binding to DNA of bacteria.
In animal and cell culture studies, berberine has demonstrated an ability to support the intestinal microenvironment.1 In a human Caco-2 cell model, berberine exhibited an ability to maintain tight junctions and support epithelial barrier function.
Ingredients
Serving Size: 2 Capsules
Amount per Serving
- Total Carbohydrate – <1 g  <1%â€
- Barberry Blend: Barberry (Berberis vulgaris) (root) Extract, Indian Barberry (berberis aristata) (root) Extract – 400 mg
- Oregon Grape (Berberis aquifolium) (root, stem) Extract – 400 mg
- Goldenseal (Hydrastis canadensis) (root, rhizome) Extract standardized to 5% total alkaloids including berberine and hydrastine (5mg) – 100 mg
Other Ingredients:Â plant-derived capsule (hypromellose), cellulose, magnesium stearate, silica
Directions
Adults take 2 capsules three times daily with food, or as recommended by a healthcare professional.
Warning
Do not use if you are pregnant or nursing. If you have diabetes or if you are taking any medications, consult a healthcare professional before use. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.
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