Table of Contents
5-MTHF
5-MTHF by Thorne is a bioactive, methylated form of folate, an essential B vitamin that supports healthy methylation, and is suitable for individuals with MTHFR gene variations.
Ingredient Information
Key Ingredients
Ingredient Amounts
| Name | Amount |
|---|---|
| Folate (L-5-MTHF) | 1.7/8.3 mg DFE |
| Other Ingredients: Hypromellose Capsule, Leucine, Microcrystalline Cellulose, Silicon Dioxide |
How to Use
Take 1 capsule one to three times daily or as recommended by one of our health professionals.
5-MTHF Details
Folate is a key component in the body’s methylation cycle, a series of biochemical reactions that play a beneficial role in multiple body systems. Healthy methylation supports cellular energy production, healthy metabolic function, and overall wellness.
Approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally. For these individuals, methylated vitamins like Thorne’s provide essential nutritional support.
Benefits:
- Nutritional support for individuals who have an MTHFR gene variation
- Supports healthy neurological function and overall neurological wellness
- Supports healthy methylation cycle function and healthy homocysteine levels already in the normal range
- Suitable for use during pregnancy when recommended by a healthcare provider
- Supports overall cellular wellness
Features:
- Suitable for individuals who have an MTHFR gene variation
- Active, methylated folate means your body gets the highest benefit with the least additional work
- 1 mg is recommended for support during pregnancy
- Easy-to-take, small capsules
Warnings
Allergy Warning
Not recommended for individuals with known sensitivity to any ingredient.
Pregnancy Warning
If pregnant, consult your health professional before using this product.
Interactions
5-MTHF supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with its therapeutic activity. An individual taking methotrexate for inflammatory conditions can safely take a supplement containing folate.








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