Table of Contents
5-MTHF
5-MTHF by Thorne is a bioactive, methylated form of folate, an essential B vitamin that supports heart, brain, blood, and bone health and is suitable for individuals with MTFHR gene mutations.
Ingredient Information
Key Ingredients
Ingredient Amounts
| Name | Amount |
|---|---|
| Folate (L-5-MTHF) | 1.7/8.3 mg DFE |
| Other Ingredients: Hypromellose Capsule, Leucine, Microcrystalline Cellulose, Silicon Dioxide |
How to Use
Take 1 capsule one to three times daily or as recommended by one of our health coach professionals.
5-MTHF Details
Folate is a key component in the body’s methylation cycle, a series of biochemical reactions that play a beneficial role in multiple body systems. Heart and brain health, cellular energy production, fat metabolism, liver detoxification, and bone health all rely on a healthy methylation cycle.
Approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally. For these individuals, methylated vitamins, like Thorne’s, provide essential nutritional support.
Benefits:
- Nutritional support for individuals who have an MTHFR gene mutation
- Supports production of key neurotransmitters – serotonin, melatonin, dopamine, and epinephrine – natural brain chemicals that play an important role in regulating brain function and mood
- Promotes cardiovascular, brain, and bone health by maintaining a healthy methylation cycle and a normal homocysteine level
- Supports healthy fetal brain and spinal cord development
- Promotes blood and nerve cell health
Features:
- Suitable for individuals who have an MTHFR gene mutation
- Active, methylated folate (5-MTHF) means your body gets the highest benefit with the least additional work
- 1 mg 5-MTHF is recommended for support of fetal development during pregnancy
- Easy-to-take, small capsules
Warnings
Allergy Warning
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
Pregnancy Warning
If pregnant, consult your health professional before using this product.
Interactions
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate’s anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate.
An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
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